Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526815 | 1.00 | CA1 (0.43) | CA1CA2CA7CA14TSHR | |
| SCHEMBL29920805 | 0.82 | CA1 (0.41) | CA1CA2CA7CA14TSHR | |
| SCHEMBL28876492 | 0.80 | CA1 (0.40) | CA1CA2CA7CA14TSHR | |
| SCHEMBL21575128 | 0.80 | CA2 (0.45) | CA1CA2CA7CA14TSHR | |
| SCHEMBL21992098 | 0.80 | CA1 (0.40) | CA1CA2CA7CA14 | |
| SCHEMBL14453098 | 0.80 | CA2 (0.45) | CA1CA2CA7CA14TSHR | |
| SCHEMBL15672774 | 0.80 | CA1 (0.40) | CA1CA2CA7CA14 | |
| SCHEMBL13583496 | 0.78 | CA1 (0.39) | CA1CA2 | |
| SCHEMBL5266419 | 0.78 | CA1 (0.39) | CA1CA2EPHX1 | |
| SCHEMBL14534529 | 0.77 | CA1 (0.37) | CA1CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190125701-A1 | Compositions and Methods for Treating Viral Infection in Mammals | UNIV YALE (US) | 2019-05-02 | — | — | US | claimed |
| EP-3452172-A1 | COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION IN MAMMALS | Yale University (US) | 2019-03-13 | — | — | EP | claimed |
| WO-2017192799-A1 | COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION IN MAMMALS | YALE UNIVERSITY (US) | 2017-11-09 | — | — | WO | claimed |
| US-11174271-B2 | 6-membered uracil isosteres | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2021-11-16 | — | — | US | disclosed |
| US-20190270756-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2019-09-05 | — | — | US | disclosed |
| US-20190125701-A1 | Compositions and Methods for Treating Viral Infection in Mammals | UNIV YALE (US) | 2019-05-02 | — | — | US | disclosed |
| US-20190125701-A1 | Compositions and Methods for Treating Viral Infection in Mammals | UNIV YALE (US) | 2019-05-02 | — | — | US | disclosed |
| EP-3452172-A1 | COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION IN MAMMALS | Yale University (US) | 2019-03-13 | — | — | EP | disclosed |
| WO-2019036679-A1 | COMPOSITIONS COMPRISING AROMATIC COMPOUNDS FOR USE IN OIL AND/OR GAS WELLS AND RELATED METHODS | FLOTEK CHEMISTRY, LLC (US) | 2019-02-21 | — | — | WO | disclosed |
| CN-108431135-A | The manufacturing method of resin combination, the manufacturing method of resin, the manufacturing method of resin film and electronic equipment | 东丽株式会社 | 2018-08-21 | — | — | CN | disclosed |
| WO-2017192799-A1 | COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION IN MAMMALS | YALE UNIVERSITY (US) | 2017-11-09 | — | — | WO | disclosed |
| EP-1845090-A1 | AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | Nissan Chemical Industries, Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |
| CN-1798739-A | 3-alkylidenehydrazino substituted heteroaryl compounds as thrombopoietin receptor activators | NISSAN CHEMICAL IND LTD (JP) | 2006-07-05 | — | — | CN | disclosed |
| US-20060094694-A1 | Heterocyclic compounds and thrombopoietin receptor activators | NISSAN CHEMICAL INDUSTRIES LIMITED (JP) | 2006-05-04 | — | — | US | disclosed |
| CN-1501794-A | Cooling composition | — | 2004-06-02 | — | — | CN | disclosed |
| EP-0847988-B1 | Process for the preparation of N-hydrocarbyl-substituted amides | LUBRIZOL CORP (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2000000499-A1 | METHOD FOR PREPARING OLIGONUCLEOTIDES WITH BORANOPHOSPHATE LINKAGES | ISIS PHARMACEUTICALS, INC. (US) | 2000-01-06 | — | — | WO | disclosed |
| EP-0847988-A1 | Process for the preparation of N-hydrocarbyl-substituted amides | The Lubrizol Corporation (US) | 1998-06-17 | — | — | EP | disclosed |
| US-5712413-A | Process for the preparation of N-hydrocarbyl-substituted amides such as tert-butylacrylamide via the Ritter reaction using solid heteropolyacid catalysts | THE LUBRIZOL CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| CN-1084387-A | Coolant compositions | PROCTER & GAMBLE (US) | 1994-03-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094694-A1 | Heterocyclic compounds and thrombopoietin receptor activators | NR2C2, ROR1, NR0B2 | CA1 2516/4885CA2 2631/4885CA7 3539/4885 |
| US-11174271-B2 | 6-membered uracil isosteres | UNG, DUT, DPYD | CA1 3556/4885CA2 4284/4885CA7 2711/4885 |
| US-20190270756-A1 | 6-MEMBERED URACIL ISOSTERES | UNG, DUT, DPYD | CA1 3556/4885CA2 4284/4885CA7 2711/4885 |
| US-20190125701-A1 | Compositions and Methods for Treating Viral Infection in Mammals | RPL35, PIGS, HAVCR2 | CA1 334/4885CA2 718/4885CA7 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.