SCHEMBL3078162

SCHEMBL3078162

c1cncc(-c2cc(-c3cccnc3)[nH]n2)c1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.89
ALDH1A1 P00352 2/20 0.89
CYP1A2 P05177 2/20 0.89
HPGDS O60760 2/20 0.72
ALK Q9UM73 1/20 0.67
CYP2A6 P11509 4/20 0.61
CYP2B6 P20813 3/20 0.61
CYP2D6 P10635 2/20 0.61
CYP2C9 P11712 2/20 0.61
CYP2C19 P33261 2/20 0.61
POLB P06746 1/20 0.58
RAB9A P51151 1/20 0.58
CYP2E1 P05181 2/20 0.55
METAP2 P50579 1/20 0.53
SIRT3 Q9NTG7 1/20 0.53
PIM1 P11309 5/20 0.51
BTK Q06187 1/20 0.50
PIM3 Q86V86 3/20 0.49
PIM2 Q9P1W9 3/20 0.49
CYP19A1 P11511 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27730924 0.93 HPGDS (0.78) CYP3A4ALDH1A1CYP1A2HPGDSALK
SCHEMBL17279983 0.93 CYP3A4 (0.77) CYP3A4ALDH1A1CYP1A2HPGDSALK
SCHEMBL27955840 0.91 CYP3A4 (0.75) CYP3A4ALDH1A1CYP1A2HPGDSALK
Hydrochloric Acid SCHEMBL27514609 0.91 HPGDS (0.76) CYP3A4ALDH1A1CYP1A2HPGDSALK
SCHEMBL2316526 0.85 HPGDS (0.89) CYP3A4ALDH1A1CYP1A2HPGDSALK
SCHEMBL2837635 0.85 HPGDS (1.00) CYP3A4ALDH1A1CYP1A2HPGDSALK
SCHEMBL27955857 0.82 ALDH1A1 (0.61) CYP3A4ALDH1A1CYP1A2HPGDSALK
SCHEMBL28207587 0.81 ALDH1A1 (0.61) CYP3A4ALDH1A1CYP1A2HPGDSALK
SCHEMBL20099873 0.81 CYP3A4 (0.60) CYP3A4ALDH1A1CYP1A2HPGDSALK
SCHEMBL17938573 0.81 ALDH1A1 (0.60) CYP3A4ALDH1A1CYP1A2HPGDSALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104860927-A 1H-3,5-bis(3-pyridinyl)-4-chloropyrazole compound, and preparation method and application thereof UNIV NINGBO 2015-08-26 CN claimed
CN-104860927-A 1H-3,5-bis(3-pyridinyl)-4-chloropyrazole compound, and preparation method and application thereof UNIV NINGBO 2015-08-26 CN disclosed
CN-104860927-A 1H-3,5-bis(3-pyridinyl)-4-chloropyrazole compound, and preparation method and application thereof UNIV NINGBO 2015-08-26 CN disclosed
US-7833331-B2 Non-toxic corrosion-protection pigments based on cobalt UNIVERSITY OF DAYTON (US) 2010-11-16 US disclosed
US-7789958-B2 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON (US) 2010-09-07 US disclosed
US-20090163628-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON COBALT STURGILL JEFFREY ALLEN 2009-06-25 US disclosed
US-7537663-B2 Corrosion-inhibiting coating UNIVERSITY OF DAYTON (US) 2009-05-26 US disclosed
US-7422793-B2 Non-toxic corrosion-protection rinses and seals based on rare earth elements UNIVERSITY OF DAYTON (US) 2008-09-09 US disclosed
US-7407711-B2 Non-toxic corrosion-protection conversion coats based on rare earth elements UNIVERSITY OF DAYTON (US) 2008-08-05 US disclosed
US-7294211-B2 Non-toxic corrosion-protection conversion coats based on cobalt UNIVERSITY OF DAYTON (US) 2007-11-13 US disclosed
US-20040020568-A1 Non-toxic corrosion-protection conversion coats based on rare earth elements DAYTON, UNIVERSITY OF 2004-02-05 US disclosed
US-20040016363-A1 CORROSION-INHIBITING COATING VENTURE LENDING & LEASING, IV, INC. 2004-01-29 US disclosed
WO-2004009869-A2 CORROSION-INHIBITING COATING FOR METAL SURFACES UNIVERSITY OF DAYTON (US) 2004-01-29 WO disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed