Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 14/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 12/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30782888 | 0.99 | CYP11B2 (0.46) | CYP11B2CYP11B1HRH3ADRA2AADRA2B | |
| SCHEMBL23641227 | 0.81 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL30782881 | 0.80 | SLC6A4 (0.41) | CYP11B2CYP11B1HRH3ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL30782892 | 0.77 | TAAR1 (0.41) | CYP11B2CYP11B1HRH3ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL30782839 | 0.77 | TAAR1 (0.41) | CYP11B2CYP11B1HRH3ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL30782891 | 0.77 | SLC6A4 (0.41) | HRH3ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL19831763 | 0.75 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL30782874 | 0.73 | CYP11B2 (0.41) | CYP11B2CYP11B1HRH3LAP3 | |
| SCHEMBL22905344 | 0.72 | KDM4C (0.52) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL9520419 | 0.71 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4593954-A1 | COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI Drug Discovery LLC (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073383-A1 | COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI DRUG DISCOVERY LLC (US) | 2024-04-04 | — | — | WO | disclosed |