SCHEMBL30783201

SCHEMBL30783201

NC(=O)CCOc1ncccc1C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.45
WNT3A P56704 1/20 0.45
SSTR4 P31391 17/20 0.44
SSTR1 P30872 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17558277 1.00 CTNNB1 (0.45) CTNNB1WNT3ASSTR4SSTR1
SCHEMBL30783171 0.80 SSTR4 (0.45) SSTR4SSTR1
SCHEMBL17848476 0.80 SCN9A (0.46) CTNNB1WNT3ASSTR4SSTR1
SCHEMBL2635568 0.78 KIF11 (0.42) CTNNB1WNT3ASSTR4SSTR1
SCHEMBL28906606 0.77 SSTR4 (0.57) SSTR4SSTR1
SCHEMBL1116787 0.77 RXRA (0.51)
SCHEMBL20797342 0.77 SSTR4 (0.46) SSTR4SSTR1
Hydrochloric Acid SCHEMBL26136590 0.77 TRPV1 (0.41) SSTR4SSTR1
SCHEMBL15677613 0.76 SLC22A12 (0.44) SSTR4SSTR1
SCHEMBL16269345 0.76 SSTR4 (0.47) CTNNB1WNT3ASSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112236423-B Piperidinyl-3- (aryloxy) propanamides and propionic acid esters 武田药品工业株式会社 2024-02-06 CN disclosed