Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23203435 | 1.00 | MAPT (0.60) | MAPTVCAM1SMN1; SMN2NPC1HTT | |
| SCHEMBL18578297 | 0.85 | MAPT (0.60) | MAPTVCAM1SMN1; SMN2NPC1HTT | |
| SCHEMBL11649718 | 0.79 | SERPINE1 (0.56) | MAPTVCAM1SMN1; SMN2NPC1HTT | |
| SCHEMBL711751 | 0.79 | MAPT (0.62) | MAPTVCAM1SMN1; SMN2HTTLMNA | |
| SCHEMBL9988774 | 0.79 | LMNA (0.50) | MAPTSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL30526834 | 0.79 | LMNA (0.50) | MAPTSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL30305918 | 0.78 | MAPT (0.60) | MAPTVCAM1SMN1; SMN2NPC1HTT | |
| SCHEMBL11039125 | 0.78 | CA12 (0.61) | MAPTVCAM1SMN1; SMN2NPC1HTT | |
| SCHEMBL2111996 | 0.78 | VCAM1 (0.54) | MAPTVCAM1SMN1; SMN2NPC1HTT | |
| SCHEMBL2113235 | 0.78 | MAPT (0.60) | MAPTVCAM1SMN1; SMN2NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236416-B | Pyrimidine cyclohexenyl glucocorticoid receptor modulators | 科赛普特治疗公司 | 2024-03-01 | — | — | CN | disclosed |