Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.40 |
| ▸ | KDM4A | O75164 | 6/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.40 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4090613 | 1.00 | DNM1 (0.55) | DNM1THRBFNTAFNTBPGGT1B | |
| Bromide SCHEMBL16824527 | 1.00 | DNM1 (0.55) | DNM1THRBFNTAFNTBPGGT1B | |
| Dymanthine SCHEMBL307460 | 1.00 | DNM1 (0.55) | DNM1THRBFNTAFNTBPGGT1B | |
| SCHEMBL1476520 | 0.98 | DNM1 (0.54) | DNM1THRBFNTAFNTBPGGT1B | |
| SCHEMBL16824248 | 0.98 | DNM1 (0.54) | DNM1THRBFNTAFNTBPGGT1B | |
| SCHEMBL1478483 | 0.98 | DNM1 (0.54) | DNM1THRBFNTAFNTBPGGT1B | |
| Dymanthine SCHEMBL1476823 | 0.98 | DNM1 (0.54) | DNM1THRBFNTAFNTBPGGT1B | |
| SCHEMBL4931015 | 0.98 | DNM1 (0.54) | DNM1THRBFNTAFNTBPGGT1B | |
| SCHEMBL1476849 | 0.91 | DNM1 (0.42) | DNM1THRBFNTAFNTBPGGT1B | |
| Dymanthine SCHEMBL3148088 | 0.90 | DNM1 (0.44) | DNM1THRBFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600900-B2 | Acidizing compositions for improved fluid performance | HALLIBURTON ENERGY SERVICES, INC. (US) | 2026-04-14 | — | — | US | claimed |
| US-20230416598-A1 | ACIDIZING COMPOSITIONS FOR IMPROVED FLUID PERFORMANCE | HALLIBURTON ENERGY SERVICES, INC. (US) | 2023-12-28 | — | — | US | claimed |
| US-11787999-B2 | Acidizing compositions for improved fluid performance | HALLIBURTON ENERGY SERVICES, INC. (US) | 2023-10-17 | — | — | US | claimed |
| US-11608461-B2 | Conformance for carbonate formations | HALLIBURTON ENERGY SERVICES, INC. (US) | 2023-03-21 | — | — | US | claimed |
| WO-2022071991-A1 | CONFORMANCE FOR CARBONATE FORMATIONS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2022-04-07 | — | — | WO | claimed |
| US-20220098465-A1 | CONFORMANCE FOR CARBONATE FORMATIONS | HALLIBURTON ENERGY SERVICES, INC. | 2022-03-31 | — | — | US | claimed |
| US-9598631-B2 | Sulfonated relative permeability modifiers for reducing subterranean formation water permeability | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-03-21 | — | — | US | claimed |
| US-20170002262-A1 | SULFONATED RELATIVE PERMEABILITY MODIFIERS FOR REDUCING SUBTERRANEAN FORMATION WATER PERMEABILITY | HALIBURTON ENERGY SERVICES, INC. (US) | 2017-01-05 | — | — | US | claimed |
| EP-1193365-B1 | Reducing subterranean formation water permeability | HALLIBURTON ENERGY SERV INC (US) | 2014-12-03 | — | — | EP | claimed |
| US-7687438-B2 | Drill-in fluids and associated methods | HALLIBURTON ENERGY SERVICES, INC. (US) | 2010-03-30 | — | — | US | claimed |
| US-7678743-B2 | Drill-in fluids and associated methods | HALLIBURTON ENERGY SERVICES, INC. (US) | 2010-03-16 | — | — | US | claimed |
| US-7678742-B2 | Drill-in fluids and associated methods | HALLIBURTON ENERGY SERVICES, INC. (US) | 2010-03-16 | — | — | US | claimed |
| US-20080070808-A1 | Drill-in fluids and associated methods | HALLIBURTON ENERGY SERVICES, INC. | 2008-03-20 | — | — | US | claimed |
| US-20080070807-A1 | Drill-in fluids and associated methods | HALLIBURTON ENERGY SERVICES, INC. | 2008-03-20 | — | — | US | claimed |
| US-20080070805-A1 | Drill-in fluids and associated methods | HALLIBURTON ENERGY SERVICES, INC. | 2008-03-20 | — | — | US | claimed |
| US-7114568-B2 | Hydrophobically modified polymers for a well completion spacer fluid | HALLIBURTON ENERGY SERVICES, INC. (US) | 2006-10-03 | — | — | US | claimed |
| US-20050230116-A1 | Methods and compositions for use with spacer fluids used in subterranean well bores | HALLIBURTON ENERGY SERVICES, INC. | 2005-10-20 | — | — | US | claimed |
| US-20050178549-A1 | Methods of reducing the permeabilities of horizontal well bore sections | HALLIBURTON ENERGY SERVICES, INC. | 2005-08-18 | — | — | US | claimed |
| WO-2004076811-A2 | DRILLING FLUID COMPONENT | HALLIBURTON ENERGY SERVICES, INC. (US) | 2004-09-10 | — | — | WO | claimed |
| US-20040171495-A1 | Drilling fluid component | HALLIBURTON ENERGY SERVICES, INC. | 2004-09-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12600900-B2 | Acidizing compositions for improved fluid performance | PHOSPHO1, PMM2, ACP1 | DNM1 926/4885THRB 752/4885FNTA 4062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.