Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.40 |
| ▸ | KDM4A | O75164 | 6/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.40 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL307833 | 1.00 | DNM1 (0.55) | DNM1THRBFNTAFNTBPGGT1B | |
| Bromide SCHEMBL16824527 | 1.00 | DNM1 (0.55) | DNM1THRBFNTAFNTBPGGT1B | |
| Dymanthine SCHEMBL307460 | 1.00 | DNM1 (0.55) | DNM1THRBFNTAFNTBPGGT1B | |
| SCHEMBL1476520 | 0.98 | DNM1 (0.54) | DNM1THRBFNTAFNTBPGGT1B | |
| SCHEMBL16824248 | 0.98 | DNM1 (0.54) | DNM1THRBFNTAFNTBPGGT1B | |
| SCHEMBL1478483 | 0.98 | DNM1 (0.54) | DNM1THRBFNTAFNTBPGGT1B | |
| Dymanthine SCHEMBL1476823 | 0.98 | DNM1 (0.54) | DNM1THRBFNTAFNTBPGGT1B | |
| SCHEMBL4931015 | 0.98 | DNM1 (0.54) | DNM1THRBFNTAFNTBPGGT1B | |
| SCHEMBL1476849 | 0.91 | DNM1 (0.42) | DNM1THRBFNTAFNTBPGGT1B | |
| Dymanthine SCHEMBL3148088 | 0.90 | DNM1 (0.44) | DNM1THRBFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9247736-B2 | Antimicrobial adhesive films | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-02-02 | — | — | US | claimed |
| US-20240114905-A1 | ANTIMICROBIAL COMPOSITIONS AND ARTICLES AND RELATED METHODS | 3M INNOVATIVE PROPERTIES COMPANY | 2024-04-11 | — | — | US | disclosed |
| EP-4284176-A1 | ANTIMICROBIAL COMPOSITIONS AND ARTICLES AND RELATED METHODS | 3M Innovative Properties Company (US) | 2023-12-06 | — | — | EP | disclosed |
| WO-2022162614-A1 | ANTIMICROBIAL COMPOSITIONS AND ARTICLES AND RELATED METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-08-04 | — | — | WO | disclosed |
| US-20220228005-A1 | Aqueous-Based Release Coatings and Article Therefrom | 3M INNOVATIVE PROPERTIES COMPANY | 2022-07-21 | — | — | US | disclosed |
| EP-3990502-A1 | AQUEOUS-BASED RELEASE COATINGS AND ARTICLES THEREFROM | 3M Innovative Properties Company (US) | 2022-05-04 | — | — | EP | disclosed |
| WO-2020261037-A1 | AQUEOUS-BASED RELEASE COATINGS AND ARTICLES THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-12-30 | — | — | WO | disclosed |
| EP-3083862-B1 | ANTIMICROBIAL PRESSURE-SENSITIVE ADHESIVE SYSTEM | 3M INNOVATIVE PROPERTIES CO (US) | 2020-08-05 | — | — | EP | disclosed |
| US-20170007464-A1 | ANTIMICROBIAL PRESSURE-SENSITIVE ADHESIVE SYSTEM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-01-12 | — | — | US | disclosed |
| US-20160310631-A1 | ANTIMICROBIAL FIBROUS MATERIALS AND METHODS OF MAKING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-10-27 | — | — | US | disclosed |
| EP-3083862-A1 | ANTIMICROBIAL PRESSURE-SENSITIVE ADHESIVE SYSTEM | 3M Innovative Properties Company (US) | 2016-10-26 | — | — | EP | disclosed |
| EP-3016513-A1 | ANTIMICROBIAL FOAMS AND METHODS OF MAKING SAME | 3M Innovative Properties Company (US) | 2016-05-11 | — | — | EP | disclosed |
| US-20160120176-A1 | ANTIMICROBIAL FOAMS AND METHODS OF MAKING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-05-05 | — | — | US | disclosed |
| US-9247736-B2 | Antimicrobial adhesive films | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-02-02 | — | — | US | disclosed |
| WO-2015094786-A1 | ANTIMICROBIAL FIBROUS MATERIALS AND METHODS OF MAKING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015095165-A1 | ANTIMICROBIAL PRESSURE-SENSITIVE ADHESIVE SYSTEM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015002786-A1 | ANTIMICROBIAL FOAMS AND METHODS OF MAKING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-01-08 | — | — | WO | disclosed |
| US-20090130157-A1 | Antimicrobial Adhesive Films | 3M INNOVATIVE PROPERTIES COMPANY | 2009-05-21 | — | — | US | disclosed |
| WO-2007070650-A2 | ANTIMICROBIAL ADHESIVE FILMS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130157-A1 | Antimicrobial Adhesive Films | ICAM1, EPCAM, CAPG | DNM1 622/4885THRB 4437/4885FNTA 3407/4885 |
| US-20160120176-A1 | ANTIMICROBIAL FOAMS AND METHODS OF MAKING SAME | CUTA, ARG1, CD68 | DNM1 628/4885THRB 4807/4885FNTA 4110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.