Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 9/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27262630 | 1.00 | TDP1 (0.51) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL27261432 | 0.91 | TDP1 (0.51) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL15706357 | 0.90 | NPSR1 (0.51) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL15706327 | 0.90 | NPSR1 (0.51) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL8602068 | 0.89 | TDP1 (0.48) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL12852254 | 0.88 | CA1 (0.49) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL15706349 | 0.88 | POLB (0.49) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL30898863 | 0.85 | MEN1 (0.56) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL30783472 | 0.85 | NOD1 (0.48) | TDP1ATMNPSR1KMT2AMEN1 | |
| SCHEMBL27261378 | 0.85 | NOD1 (0.48) | TDP1ATMNPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561998-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | Ratio Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026072-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | RATIO THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |