Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27261378 | 1.00 | NOD1 (0.48) | NOD1TDP1ATMPOLBNPSR1 | |
| SCHEMBL15706327 | 0.93 | NPSR1 (0.51) | NOD1TDP1ATMPOLBNPSR1 | |
| SCHEMBL15706357 | 0.93 | NPSR1 (0.51) | NOD1TDP1ATMPOLBNPSR1 | |
| SCHEMBL30019660 | 0.91 | NOD1 (0.50) | NOD1DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL15706349 | 0.91 | POLB (0.49) | NOD1TDP1ATMPOLBNPSR1 | |
| SCHEMBL27148691 | 0.88 | NOD1 (0.49) | NOD1DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL30020885 | 0.87 | GNAI3 (0.57) | NOD1TDP1MEN1KMT2ADPP7 | |
| SCHEMBL30020812 | 0.86 | GLP1R (0.46) | NOD1DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL30020169 | 0.85 | NOD1 (0.49) | NOD1DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL30783499 | 0.85 | TDP1 (0.51) | TDP1ATMPOLBNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561998-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | Ratio Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2025029608-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | RATIO THERAPEUTICS, INC. (US) | 2025-02-06 | — | — | WO | disclosed |
| WO-2024026072-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | RATIO THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |