Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | PRKDC | P78527 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783583 | 0.86 | AKT1 (0.47) | HTTPRKDCDRD2DRD4DRD3 | |
| SCHEMBL30783794 | 0.86 | HTT (0.40) | DPP4HTTALDH1A1KDM4EHPGD | |
| SCHEMBL30784348 | 0.86 | AKT1 (0.47) | HTTPRKDCDRD2DRD4DRD3 | |
| SCHEMBL30783695 | 0.85 | HTT (0.39) | DPP4HTTALDH1A1KDM4EHPGD | |
| SCHEMBL30783830 | 0.85 | HTT (0.39) | DPP4HTTALDH1A1KDM4EHPGD | |
| SCHEMBL30784396 | 0.85 | HTT (0.39) | DPP4HTTALDH1A1KDM4EHPGD | |
| SCHEMBL30784172 | 0.85 | HTT (0.39) | DPP4HTTALDH1A1KDM4EHPGD | |
| SCHEMBL30784281 | 0.83 | DPP4 (0.45) | DPP4HTTALDH1A1KDM4EHPGD | |
| SCHEMBL30784462 | 0.82 | SOS1 (0.42) | HTTALDH1A1KDM4ESMN1; SMN2DRD2 | |
| SCHEMBL30784478 | 0.82 | AKT1 (0.44) | HTTPRKDCPIK3CBAKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |