Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 4/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.36 |
| ▸ | HAT1 | O14929 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 4/20 | 0.34 |
| ▸ | JAK2 | O60674 | 3/20 | 0.34 |
| ▸ | TYK2 | P29597 | 3/20 | 0.34 |
| ▸ | JAK3 | P52333 | 3/20 | 0.34 |
| ▸ | USP1 | O94782 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009616 | 1.00 | KDM5A (0.40) | KDM5AALDH1A1L3MBTL1IKBKETBK1 | |
| SCHEMBL31009597 | 1.00 | KDM5A (0.40) | KDM5AALDH1A1L3MBTL1IKBKETBK1 | |
| SCHEMBL31009725 | 0.93 | IKBKE (0.36) | KDM5AALDH1A1L3MBTL1IKBKETBK1 | |
| SCHEMBL31009589 | 0.93 | IKBKE (0.36) | KDM5AALDH1A1L3MBTL1IKBKETBK1 | |
| SCHEMBL31009657 | 0.85 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1HAT1EP300FEN1 | |
| SCHEMBL31009656 | 0.85 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1HAT1EP300FEN1 | |
| SCHEMBL31009642 | 0.80 | CYP1A2 (0.42) | ALDH1A1IKBKETBK1JAK1JAK2 | |
| SCHEMBL31009626 | 0.80 | CYP1A2 (0.42) | ALDH1A1IKBKETBK1JAK1JAK2 | |
| SCHEMBL31009677 | 0.80 | EP300 (0.37) | ALDH1A1L3MBTL1EP300CREBBP | |
| SCHEMBL31009599 | 0.79 | CREBBP (0.39) | ALDH1A1L3MBTL1CREBBPJAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545754-A | Modulators of TREX1 | 星座制药公司 | 2024-02-09 | — | — | CN | disclosed |