SCHEMBL30784891

SCHEMBL30784891

CCCCc1ccc(-c2nnc(-c3ccccc3-c3ccccc3)n2-c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.66
UCHL3 P15374 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.52
HPGD P15428 1/20 0.52
AVPR1A P37288 1/20 0.49
TSHR P16473 2/20 0.46
PSMB5 P28074 1/20 0.45
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
GLA P06280 1/20 0.41
AGTR1 P30556 1/20 0.41
AGTR2 P50052 1/20 0.41
AKT1 P31749 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27752152 0.92 HSD11B1 (0.73) HSD11B1UCHL3SMN1; SMN2HPGDAVPR1A
SCHEMBL195220 0.92 HSD11B1 (0.73) HSD11B1UCHL3SMN1; SMN2HPGDAVPR1A
SCHEMBL23846180 0.92 HSD11B1 (0.72) HSD11B1UCHL3SMN1; SMN2HPGDAVPR1A
SCHEMBL21562239 0.84 HSD11B1 (0.52) HSD11B1UCHL3SMN1; SMN2HPGDAVPR1A
SCHEMBL14975277 0.83 HSD11B1 (0.60) HSD11B1UCHL3SMN1; SMN2HPGDAVPR1A
SCHEMBL10111051 0.82 HSD11B1 (0.63) HSD11B1UCHL3SMN1; SMN2HPGDAVPR1A
SCHEMBL17023639 0.81 AVPR1A (0.59) SMN1; SMN2HPGDAVPR1ATSHRKDM4E
SCHEMBL11512580 0.81 HSD11B1 (0.62) HSD11B1HPGDPSMB5ALDH1A1HSD17B10
SCHEMBL14533545 0.81 HSD11B1 (0.64) HSD11B1UCHL3SMN1; SMN2HPGDAVPR1A
SCHEMBL10035324 0.80 HSD11B1 (0.60) HSD11B1UCHL3SMN1; SMN2HPGDAVPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917882-B2 Light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11917882-B2 Light-emitting device, electronic device, and lighting device CYBA, NR2E3, ESR1 HSD11B1 2807/4885UCHL3 1600/4885SMN1; SMN2 4532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.