SCHEMBL14975277

SCHEMBL14975277

CCCCc1ccc(-c2nnc(-c3ccc(C(C)(C)C)cc3)n2-c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.60
UCHL3 P15374 2/20 0.53
RXRA P19793 1/20 0.51
RXRB P28702 1/20 0.51
RXRG P48443 1/20 0.51
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
AVPR1A P37288 1/20 0.44
OPRD1 P41143 3/20 0.44
OPRM1 P35372 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.40
TMEM97 Q5BJF2 1/20 0.40
SIGMAR1 Q99720 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23846180 0.91 HSD11B1 (0.72) HSD11B1UCHL3HPGDSMN1; SMN2AVPR1A
SCHEMBL27752152 0.88 HSD11B1 (0.73) HSD11B1UCHL3HPGDSMN1; SMN2AVPR1A
SCHEMBL195220 0.88 HSD11B1 (0.73) HSD11B1UCHL3HPGDSMN1; SMN2AVPR1A
SCHEMBL44434 0.85 RXRA (0.60) RXRARXRBRXRGHPGDSMN1; SMN2
SCHEMBL6297034 0.85 RXRA (0.60) RXRARXRBRXRGHPGDSMN1; SMN2
SCHEMBL7807503 0.83 AVPR1A (0.62) RXRARXRBRXRGHPGDSMN1; SMN2
SCHEMBL15746017 0.83 AVPR1A (0.62) RXRARXRBRXRGHPGDSMN1; SMN2
SCHEMBL30784891 0.83 HSD11B1 (0.66) HSD11B1UCHL3HPGDSMN1; SMN2AVPR1A
SCHEMBL1339833 0.82 OPRD1 (0.53) HSD11B1RXRARXRBRXRGHPGD
SCHEMBL7731514 0.82 HSD11B1 (0.47) HSD11B1UCHL3RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210384462-A1 Sealed Structure, Light-Emitting Device, Electronic Device, And Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-12-09 US disclosed
US-10361392-B2 Sealed structure, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-07-23 US disclosed
US-20160104864-A1 Sealed Structure, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-04-14 US disclosed
US-9216557-B2 Sealed structure, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-12-22 US disclosed
US-20130134398-A1 Sealed Structure, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-05-30 US disclosed