SCHEMBL307859

SCHEMBL307859

Cc1c(CC(=O)O)c(=O)oc2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.60
CA9 Q16790 3/20 0.60
POLB P06746 1/20 0.60
MTOR P42345 1/20 0.53
KDM4E B2RXH2 4/20 0.53
TP53 P04637 3/20 0.51
ALDH1A1 P00352 2/20 0.51
NQO1 P15559 2/20 0.51
TSHR P16473 2/20 0.51
MEN1 O00255 1/20 0.51
ABCB11 O95342 1/20 0.51
LMNA P02545 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
MAPK1 P28482 1/20 0.51
CYP2C19 P33261 1/20 0.51
KMT2A Q03164 1/20 0.51
PDE4D Q08499 1/20 0.51
PCSK7 Q16549 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9545054 0.85 KDM4E (0.69) POLBKDM4EALDH1A1TSHRMEN1
SCHEMBL10638322 0.84 NQO1 (0.73) CA12CA9KDM4ETP53ALDH1A1
SCHEMBL16231548 0.84 KDM4E (0.49) CA12CA9POLBKDM4ETP53
SCHEMBL2028248 0.82 KDM4E (0.51) CA12CA9KDM4ETP53ALDH1A1
SCHEMBL28719517 0.81 NQO1 (0.55) CA12CA9POLBTP53ALDH1A1
SCHEMBL590825 0.81 KDM4E (0.76) CA12CA9POLBKDM4ETP53
SCHEMBL29785070 0.81 KDM4E (0.76) CA12CA9POLBKDM4ETP53
SCHEMBL15873593 0.81 CA12 (0.59) CA12CA9POLBKDM4ETP53
SCHEMBL15842922 0.80 KDM4E (0.54) KDM4ETP53ALDH1A1NQO1TSHR
SCHEMBL3366386 0.80 CA12 (0.56) CA12CA9POLBMTORKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4247968-A1 USE OF DEXTRAMER IN SINGLE CELL ANALYSIS Becton, Dickinson and Company (US) 2023-09-27 EP claimed
CN-116615556-A Use of DEXTRAMER in single cell assays 贝克顿迪金森公司 2023-08-18 CN claimed
WO-2022109339-A1 USE OF DEXTRAMER IN SINGLE CELL ANALYSIS BECTON, DICKINSON AND COMPANY (US) 2022-05-27 WO claimed
US-20220064226-A1 Panel comprising Borrelia MHC multimers IMMUDEX APS (DK) 2022-03-03 US claimed
EP-2516669-A2 ENZYME ASSAYS ON A DROPLET ACTUATOR Advanced Liquid Logic, Inc. (US) 2012-10-31 EP claimed
WO-2011084703-A2 ENZYME ASSAYS ON A DROPLET ACTUATOR ADVANCED LIQUID LOGIC, INC. (US) 2011-07-14 WO claimed
WO-2026087501-A1 ANTIGEN MULTIMERS FOR DETECTION OF ANTIGEN-SPECIFIC CHIMERIC ANTIGEN RECEPTOR (CAR) T CELLS IMMUDEX APS (DK) 2026-04-30 WO disclosed
EP-4709743-A1 MHC CLASS I MOLECULES Immudex ApS (DK) 2026-03-18 EP disclosed
US-20250382335-A1 Panel comprising Borrelia MHC multimers IMMUDEX APS (DK) 2025-12-18 US disclosed
EP-4643131-A2 COMPOSITIONS AND METHODS FOR THE DETECTION OF MYCOPLASMA IDEXX LABORATORIES, INC. (US) 2025-11-05 EP disclosed
US-20250231185-A1 Coronavirus T Cell Epitopes, Megapools and Uses Thereof LA JOLLA INST FOR IMMUNOLOGY (US) 2025-07-17 US disclosed
WO-2025125477-A1 MHC CLASS I MOLECULE MATCHED NEGATIVE CONTROL REAGENTS IMMUDEX APS (DK) 2025-06-19 WO disclosed
WO-2025109111-A1 IMMUNE CELL ACTIVATING MULTIMERS IMMUDEX APS (DK) 2025-05-30 WO disclosed
CN-101612029-A Image acquiring method and device FUJIFILM CORP 2009-12-30 CN disclosed
EP-1943257-A2 FIBROBLAST ACTIVATION PROTEIN INHIBITOR COMPOUNDS AND METHODS Genentech, Inc. (US) 2008-07-16 EP disclosed
US-7176185-B2 Short peptide carrier system for cellular delivery of agent TSRL, INC. (US) 2007-02-13 US disclosed
WO-2006125227-A2 FIBROBLAST ACTIVATION PROTEIN INHIBITOR COMPOUNDS AND METHODS GENENTECH, INC. (US) 2006-11-23 WO disclosed
US-20050208140-A1 Short peptide carrier system for cellular delivery of agent TSRL, INC. 2005-09-22 US disclosed
US-5364764-A Immunoassay of HIV MOLECULAR PROBES, INC. (US) 1994-11-15 US disclosed
US-5262545-A Used to study transcriptional control sequence in the field of endocrinology, microbiology, virology, genetics and oncology MOLECULAR PROBES, INC. (US) 1993-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050208140-A1 Short peptide carrier system for cellular delivery of agent SLC43A1, DNPEP, LNPEP CA12 152/4885CA9 1296/4885POLB 3006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.