Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786081 | 0.84 | MCHR1 (0.53) | HRH3LTA4H | |
| SCHEMBL3386711 | 0.84 | CHRNB2 (0.51) | HRH3CHRNB2CHRNA4KEAP1NFE2L2 | |
| SCHEMBL30786251 | 0.78 | LTA4H (0.43) | LTA4H | |
| SCHEMBL14308132 | 0.76 | CHRNB2 (0.62) | HRH3CHRNB2CHRNA4KEAP1NFE2L2 | |
| SCHEMBL3446237 | 0.76 | HRH3 (0.58) | HRH3CHRNB2CHRNA4KEAP1NFE2L2 | |
| SCHEMBL2477752 | 0.75 | CHRNB2 (0.56) | HRH3CHRNB2CHRNA4KEAP1NFE2L2 | |
| SCHEMBL10256425 | 0.75 | CHRNB2 (0.56) | HRH3CHRNB2CHRNA4KEAP1NFE2L2 | |
| SCHEMBL18291032 | 0.75 | CHRNB2 (0.56) | HRH3CHRNB2CHRNA4KEAP1NFE2L2 | |
| SCHEMBL32666857 | 0.75 | CHRNB2 (0.56) | HRH3CHRNB2CHRNA4KEAP1NFE2L2 | |
| SCHEMBL31388561 | 0.75 | CHRNB2 (0.56) | HRH3CHRNB2CHRNA4KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260049071-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | BEYANG THERAPEUTICS CO LTD (CN) | 2026-02-19 | — | — | US | disclosed |
| EP-4556466-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | Beyang Therapeutics Co., Ltd. (CN) | 2025-05-21 | — | — | EP | disclosed |
| WO-2025082316-A1 | OPHTHALMIC FORMATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州必扬医药科技有限公司 | 2025-04-24 | — | — | WO | disclosed |
| CN-119604488-A | Protein tyrosine kinase inhibitor and medical application thereof | 苏州必扬医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260049071-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | KDR, FLT1, ERBB2 | HRH3 2004/4885CHRNB2 3285/4885CHRNA4 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.