SCHEMBL30786147

SCHEMBL30786147

CCNC(=O)c1cc(F)ccc1Sc1ccc2c(I)nn(C3CCCCO3)c2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.36
DRD2 P14416 3/20 0.33
HTR2A P28223 3/20 0.33
CA4 P22748 2/20 0.33
HTR1A P08908 1/20 0.33
KDM4E B2RXH2 3/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DGAT2 Q96PD7 1/20 0.33
SLC22A2 O15244 1/20 0.32
CYP3A4 P08684 1/20 0.32
TMEM97 Q5BJF2 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
HPGD P15428 3/20 0.31
TP53 P04637 1/20 0.31
RXFP1 Q9HBX9 2/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30786090 0.94 DRD2 (0.33) CA2DRD2HTR2ACA4HTR1A
SCHEMBL31475219 0.90 HPGD (0.41) CA2CA4KDM4EMAPTKMT2A
SCHEMBL30786098 0.89 TP53 (0.36) KMT2ADGAT2HPGDTP53ALDH1A1
SCHEMBL30786231 0.85 DGAT2 (0.35) CA2CA4KDM4EMEN1MAPT
SCHEMBL30786214 0.80 KDR (0.34) DRD2HTR2A
SCHEMBL30786226 0.80 CHEK1 (0.34) DRD2HTR2AHTR1AMEN1MAPT
SCHEMBL13446053 0.80 KDR (0.40) KDM4EMAPTDGAT2HPGDHSD17B10
SCHEMBL31475179 0.80 KDR (0.40) KDM4EMAPTDGAT2HPGDHSD17B10
SCHEMBL30786219 0.78 KDR (0.44) CA2CA4KDM4EMEN1MAPT
SCHEMBL31475210 0.77 DRD2 (0.37) DRD2HTR2AHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025082316-A1 OPHTHALMIC FORMATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 苏州必扬医药科技有限公司 2025-04-24 WO disclosed
CN-119604488-A Protein tyrosine kinase inhibitor and medical application thereof 苏州必扬医药科技有限公司 2025-03-11 CN disclosed
WO-2024032584-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF 苏州必扬医药科技有限公司 2024-02-15 WO disclosed