Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786086 | 0.94 | KDR (0.32) | KDRTTK | |
| SCHEMBL30786218 | 0.93 | KDR (0.31) | KDR | |
| SCHEMBL30786153 | 0.90 | KDR (0.36) | KDR | |
| SCHEMBL31475212 | 0.89 | KDR (0.37) | KDRTTKCNR1CNR2 | |
| SCHEMBL30786216 | 0.88 | KDR (0.37) | KDRTTKCNR1CNR2 | |
| SCHEMBL31475172 | 0.84 | GPR119 (0.32) | — | |
| SCHEMBL31475161 | 0.83 | KDR (0.34) | KDRTTK | |
| SCHEMBL31475215 | 0.83 | KDR (0.37) | KDRTTKCNR1CNR2 | |
| SCHEMBL31475194 | 0.82 | KDR (0.34) | KDRTTK | |
| SCHEMBL31475207 | 0.82 | KDR (0.36) | KDRTTKCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604488-A | Protein tyrosine kinase inhibitor and medical application thereof | 苏州必扬医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |