SCHEMBL30786181

SCHEMBL30786181

COC(=O)c1ccc(F)cc1SCc1ccc(OC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
LMNA P02545 2/20 0.46
ABL1 P00519 1/20 0.46
SRC P12931 1/20 0.46
FFAR4 Q5NUL3 1/20 0.46
PLA2G2A P14555 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
POLB P06746 1/20 0.45
KDM4E B2RXH2 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
TP53 P04637 1/20 0.43
GAA P10253 1/20 0.42
DAO P14920 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17080153 1.00 MAPT (0.46) MAPTMEN1KMT2ALMNAABL1
SCHEMBL17080132 0.90 LMNA (0.48) MAPTMEN1KMT2ALMNAABL1
SCHEMBL30786201 0.90 LMNA (0.48) MAPTMEN1KMT2ALMNAABL1
SCHEMBL17080124 0.89 KDM4E (0.52) LMNASMN1; SMN2KDM4ECYP1A2CYP2D6
SCHEMBL11826469 0.88 FFAR1 (0.47) MAPTMEN1KMT2ALMNAABL1
SCHEMBL30786144 0.88 FFAR1 (0.47) MAPTMEN1KMT2ALMNAABL1
SCHEMBL17080182 0.86 KDM4E (0.46) MAPTLMNASMN1; SMN2KDM4ECYP1A2
SCHEMBL17080139 0.86 CA1 (0.51) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL30786211 0.85 KMT2A (0.53) MAPTMEN1KMT2ALMNAABL1
SCHEMBL17080148 0.81 KDM4E (0.56) LMNASMN1; SMN2KDM4ECYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025082316-A1 OPHTHALMIC FORMATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 苏州必扬医药科技有限公司 2025-04-24 WO disclosed
WO-2024032584-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF 苏州必扬医药科技有限公司 2024-02-15 WO disclosed