Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17080132 | 1.00 | LMNA (0.48) | LMNAMAPTMEN1KMT2AABL1 | |
| SCHEMBL17080153 | 0.90 | MAPT (0.46) | LMNAMAPTMEN1KMT2AABL1 | |
| SCHEMBL30786181 | 0.90 | MAPT (0.46) | LMNAMAPTMEN1KMT2AABL1 | |
| SCHEMBL17080148 | 0.89 | KDM4E (0.56) | LMNAKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11817237 | 0.88 | FFAR1 (0.47) | LMNAMAPTMEN1KMT2AABL1 | |
| SCHEMBL3495677 | 0.88 | LMNA (0.44) | LMNAMAPTMEN1KMT2AABL1 | |
| SCHEMBL17080116 | 0.86 | KDM4E (0.46) | MAPTKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10740889 | 0.84 | MAPT (0.49) | LMNAMAPTKDM4ECYP1A2CYP2D6 | |
| SCHEMBL28326285 | 0.81 | POLB (0.58) | LMNAMAPTMEN1KMT2AABL1 | |
| SCHEMBL17080124 | 0.81 | KDM4E (0.52) | LMNAKDM4ECYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025082316-A1 | OPHTHALMIC FORMATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州必扬医药科技有限公司 | 2025-04-24 | — | — | WO | disclosed |
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |