Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786234 | 0.91 | KMT2A (0.43) | KDM4ACA2CA4ACACBACACA | |
| SCHEMBL30097021 | 0.76 | ACACB (0.46) | KDM4ACA2ACACBACACAKDM4E | |
| SCHEMBL508770 | 0.76 | ACACB (0.46) | KDM4ACA2ACACBACACAKDM4E | |
| SCHEMBL23705856 | 0.75 | GLS (0.47) | KDM4AACACBACACAGLSIDO1 | |
| SCHEMBL29085960 | 0.74 | L3MBTL1 (0.44) | KDM4ACA2CA4ACACBACACA | |
| SCHEMBL23706002 | 0.73 | KDM4A (0.44) | KDM4ACA2ACACBACACAKDM4E | |
| SCHEMBL23706109 | 0.73 | HDAC1 (0.48) | KDM4AACACBACACARAB9AALDH1A1 | |
| SCHEMBL7229830 | 0.73 | HDAC1 (0.47) | KDM4AACACBACACARAB9ANAMPT | |
| SCHEMBL16020311 | 0.73 | KDM4A (0.44) | KDM4ACA2CA4ACACBACACA | |
| SCHEMBL4678395 | 0.73 | SMN1; SMN2 (0.61) | KDM4ERAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |