Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.59 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30997309 | 0.89 | PDGFRB (0.68) | PDGFRBPDGFRAPDPK1MEN1KMT2A | |
| SCHEMBL8389350 | 0.85 | PDGFRB (0.69) | PDGFRBPDGFRAATMTLR8PDE10A | |
| SCHEMBL30997286 | 0.81 | PDGFRB (0.64) | PDGFRBPDGFRAMEN1KMT2ANPC1 | |
| SCHEMBL30997278 | 0.81 | PDGFRB (0.62) | PDGFRBPDGFRAMEN1KMT2ANPC1 | |
| SCHEMBL4299023 | 0.77 | PDGFRB (1.00) | PDGFRBPDGFRANPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29357672 | 0.76 | PDGFRB (0.96) | PDGFRBPDGFRANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24444648 | 0.74 | PDGFRB (0.59) | PDGFRBPDGFRAPDPK1EHMT2EHMT1 | |
| SCHEMBL8390390 | 0.74 | PDGFRB (0.59) | PDGFRBPDGFRATLR8PDE10ANOS1 | |
| SCHEMBL28102697 | 0.73 | PDGFRB (0.67) | PDGFRBPDGFRAPDPK1NPC1RAB9A | |
| SCHEMBL30786378 | 0.72 | HDAC6 (0.56) | PDGFRBPDGFRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924288-B | Quinolinyl-containing compound, pharmaceutical composition and application thereof | 北京普祺医药科技股份有限公司 | 2024-04-05 | — | — | CN | disclosed |