Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29547952 | 0.84 | HDAC6 (0.55) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL24240711 | 0.74 | MET (0.57) | HDAC1PDGFRBPDGFRAAURKALCK | |
| SCHEMBL4299023 | 0.73 | PDGFRB (1.00) | HDAC6PDGFRBPDGFRAPOLBMAPT | |
| SCHEMBL24240661 | 0.73 | HDAC2 (0.57) | HDAC6HDAC2HDAC10HDAC11HDAC8 | |
| SCHEMBL30786377 | 0.72 | PDGFRB (0.59) | PDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL30997309 | 0.72 | PDGFRB (0.68) | PDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL24240678 | 0.72 | HDAC2 (0.55) | HDAC6HDAC2HDAC10HDAC11HDAC8 | |
| SCHEMBL22521338 | 0.72 | HDAC2 (0.55) | HDAC6HDAC2HDAC10HDAC11HDAC8 | |
| Hydrochloric Acid SCHEMBL29357672 | 0.71 | PDGFRB (0.96) | HDAC6PDGFRBPDGFRAPOLBMAPT | |
| SCHEMBL8389350 | 0.70 | PDGFRB (0.69) | PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924288-B | Quinolinyl-containing compound, pharmaceutical composition and application thereof | 北京普祺医药科技股份有限公司 | 2024-04-05 | — | — | CN | disclosed |