Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.59 |
| ▸ | EHMT2 | Q96KQ7 | 12/20 | 0.58 |
| ▸ | EHMT1 | Q9H9B1 | 7/20 | 0.58 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29616380 | 0.88 | PDGFRB (0.57) | PDGFRBPDGFRAEHMT2EHMT1DNMT1 | |
| SCHEMBL30136402 | 0.87 | PDGFRB (0.56) | PDGFRBPDGFRAEHMT2EHMT1HRH3 | |
| SCHEMBL4380923 | 0.81 | FLT4 (0.65) | PDGFRBKDR | |
| SCHEMBL29565672 | 0.80 | EHMT2 (0.63) | EHMT2EHMT1TLR7TLR9DNMT1 | |
| SCHEMBL30499314 | 0.80 | CHKA (0.48) | PDGFRBPDGFRADRD3HRH3 | |
| SCHEMBL2152700 | 0.79 | EHMT2 (0.64) | PDGFRBPDGFRAEHMT2EHMT1DRD3 | |
| SCHEMBL5070073 | 0.79 | PDGFRB (0.59) | PDGFRBPDGFRAEHMT2DRD3HRH3 | |
| SCHEMBL199299 | 0.78 | EHMT2 (0.51) | EHMT2EHMT1TLR7TLR9DNMT1 | |
| SCHEMBL29566096 | 0.78 | EHMT2 (0.70) | EHMT2EHMT1TLR7TLR9DNMT1 | |
| SCHEMBL30544811 | 0.77 | SRC (0.57) | PDGFRBPDGFRAEHMT2EHMT1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393363-B | 4-phenoxy quinoline and N-sulfonyl amidine compound and preparation method and application thereof | 威海海洋生物医药产业技术研究院有限公司 | 2022-12-20 | — | — | CN | disclosed |
| EP-3329918-B1 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2022-05-25 | — | — | EP | disclosed |