Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 14/20 | 0.53 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23149647 | 1.00 | KDM4E (0.56) | KDM4EMAPK1L3MBTL1P4HTMP4HA1 | |
| SCHEMBL10662120 | 0.83 | HDAC1 (0.51) | KDM4EL3MBTL1MAPTMEN1ALDH1A1 | |
| SCHEMBL29939457 | 0.83 | HDAC1 (0.51) | KDM4EL3MBTL1MAPTMEN1ALDH1A1 | |
| SCHEMBL30786505 | 0.82 | ALDH1A1 (0.47) | KDM4EMIFMAPTMEN1ALDH1A1 | |
| SCHEMBL23149668 | 0.82 | ALDH1A1 (0.47) | KDM4EMIFMAPTMEN1ALDH1A1 | |
| SCHEMBL2585062 | 0.81 | KDM4E (0.68) | KDM4EMAPK1L3MBTL1P4HTMP4HA1 | |
| SCHEMBL29939525 | 0.81 | ALDH1A1 (0.46) | KDM4EL3MBTL1MIFMAPTMEN1 | |
| SCHEMBL3173315 | 0.81 | DGAT1 (0.60) | KDM4EL3MBTL1MAPTMEN1ALDH1A1 | |
| SCHEMBL3656932 | 0.81 | KMT2A (0.46) | KDM4EMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL5752823 | 0.81 | CXCR1 (0.46) | KDM4EMAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658991-B | Preparation method and application of 3, 5-disubstituted methylpyrazolo [1,5-a ] pyrimidine-7-phenolate analogue and derivative | 辽宁利锋科技开发有限公司 | 2023-12-15 | — | — | CN | disclosed |