Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 3/20 | 0.53 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 5/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30010736 | 0.87 | ACE (0.56) | SLC6A2ACEACE2 | |
| SCHEMBL7411063 | 0.86 | ACE (0.56) | NMUR2OPRK1ACEACE2 | |
| SCHEMBL8060131 | 0.86 | ACE (0.56) | NMUR2OPRK1ACEACE2 | |
| SCHEMBL29632816 | 0.86 | ACE (0.57) | OPRK1ACEACE2 | |
| SCHEMBL30886747 | 0.86 | OPRK1 (0.57) | OPRK1SLC6A2ACEACE2 | |
| SCHEMBL30203894 | 0.85 | NMUR2 (0.54) | NMUR2NMUR1OPRK1SLC6A2 | |
| SCHEMBL34461922 | 0.85 | SLC6A2 (0.57) | NMUR2NMUR1OPRK1SLC6A2 | |
| SCHEMBL7259788 | 0.85 | ACE (0.64) | ACEACE2 | |
| SCHEMBL7259790 | 0.85 | ACE (0.64) | ACEACE2 | |
| SCHEMBL29630548 | 0.85 | SLC6A2 (0.53) | SLC6A2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240042063-A1 | LINKED AND OTHER pH-TRIGGERED COMPOUNDS | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2024-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240042063-A1 | LINKED AND OTHER pH-TRIGGERED COMPOUNDS | LIPA, PHOSPHO1, NGLY1 | NMUR2 1595/4885NMUR1 1645/4885OPRK1 4743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.