Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 6/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 4/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30788011 | 0.98 | CALCRL (0.61) | CALCRLSLC6A2RAMP1KEAP1REN | |
| SCHEMBL30788021 | 0.98 | CALCRL (0.61) | CALCRLSLC6A2RAMP1KEAP1REN | |
| SCHEMBL30788025 | 0.95 | CALCRL (0.61) | CALCRLSLC6A2RAMP1KEAP1REN | |
| SCHEMBL30788010 | 0.91 | CALCRL (0.61) | CALCRLSLC6A2RAMP1RENOPRK1 | |
| SCHEMBL30586507 | 0.91 | SLC6A2 (0.57) | CALCRLSLC6A2RENOPRK1 | |
| SCHEMBL30788019 | 0.89 | SLC6A2 (0.68) | CALCRLSLC6A2 | |
| SCHEMBL29368042 | 0.88 | OPRM1 (0.56) | CALCRLSLC6A2RENOPRK1 | |
| SCHEMBL29679944 | 0.88 | CALCRL (0.56) | CALCRLSLC6A2RAMP1RENOPRK1 | |
| SCHEMBL31151838 | 0.88 | SLC6A2 (0.73) | CALCRLSLC6A2RENOPRK1 | |
| SCHEMBL6374240 | 0.87 | OPRM1 (0.52) | CALCRLSLC6A2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240042063-A1 | LINKED AND OTHER pH-TRIGGERED COMPOUNDS | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2024-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240042063-A1 | LINKED AND OTHER pH-TRIGGERED COMPOUNDS | LIPA, PHOSPHO1, NGLY1 | CALCRL 314/4885SLC6A2 3078/4885RAMP1 3913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.