Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.68 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.55 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.54 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30788025 | 0.91 | CALCRL (0.61) | SLC6A2CALCRL | |
| SCHEMBL29630334 | 0.90 | SLC6A2 (0.66) | SLC6A2CALCRLOPRM1OPRD1 | |
| SCHEMBL30788014 | 0.89 | CALCRL (0.60) | SLC6A2CALCRL | |
| SCHEMBL30788021 | 0.89 | CALCRL (0.61) | SLC6A2CALCRL | |
| SCHEMBL30788011 | 0.89 | CALCRL (0.61) | SLC6A2CALCRL | |
| SCHEMBL30518298 | 0.88 | SLC6A2 (0.66) | SLC6A2OPRM1OPRD1 | |
| SCHEMBL31020744 | 0.88 | SLC6A2 (0.63) | SLC6A2CALCRLOPRM1OPRD1NMUR2 | |
| SCHEMBL31612357 | 0.87 | SLC6A2 (0.73) | SLC6A2OPRM1OPRD1NMUR2NMUR1 | |
| SCHEMBL29531376 | 0.87 | SLC6A2 (0.72) | SLC6A2CALCRLOPRM1OPRD1 | |
| SCHEMBL29530548 | 0.87 | SLC6A2 (0.72) | SLC6A2CALCRLOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240042063-A1 | LINKED AND OTHER pH-TRIGGERED COMPOUNDS | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2024-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240042063-A1 | LINKED AND OTHER pH-TRIGGERED COMPOUNDS | LIPA, PHOSPHO1, NGLY1 | SLC6A2 3078/4885CALCRL 314/4885OPRM1 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.