SCHEMBL31020744

SCHEMBL31020744

CC(C)C[C@H](N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.63
NMUR2 Q9GZQ4 3/20 0.57
CALCRL Q16602 1/20 0.56
AGTR1 P30556 1/20 0.54
AGTR2 P50052 1/20 0.54
NMUR1 Q9HB89 2/20 0.54
NTSR2 O95665 1/20 0.53
NTSR1 P30989 1/20 0.53
OPRM1 P35372 1/20 0.53
OPRD1 P41143 1/20 0.53
KISS1R Q969F8 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30844089 0.92 KISS1R (0.64) SLC6A2OPRM1KISS1R
SCHEMBL29702226 0.91 SLC6A2 (0.62) SLC6A2CALCRLAGTR1AGTR2OPRM1
SCHEMBL30085011 0.90 SLC6A2 (0.65) SLC6A2NMUR2CALCRLNTSR2NTSR1
SCHEMBL38650937 0.90 NTSR1 (0.58) SLC6A2NMUR2NMUR1NTSR2NTSR1
SCHEMBL29796758 0.89 SLC6A2 (0.64) SLC6A2NMUR2CALCRLNMUR1NTSR2
SCHEMBL29705074 0.89 SLC6A2 (0.59) SLC6A2CALCRLNTSR2NTSR1OPRM1
SCHEMBL30209621 0.88 F2 (0.60) SLC6A2NMUR2NTSR1KISS1R
SCHEMBL30788019 0.88 SLC6A2 (0.68) SLC6A2NMUR2CALCRLNMUR1OPRM1
SCHEMBL29836567 0.87 SLC6A2 (0.60) SLC6A2NMUR2CALCRLAGTR1AGTR2
SCHEMBL29796577 0.87 SLC6A2 (0.60) SLC6A2NMUR2CALCRLAGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2847223-B2 ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME DARTMOUTH COLLEGE (US) 2025-04-09 EP disclosed
US-20250002584-A1 ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME DARTMOUTH COLLEGE (US) 2025-01-02 US disclosed
US-12065492-B2 Anti-B7-H6 antibody, fusion proteins, and methods of using the same THE TRUSTEES OF DARTMOUTH COLLEGE (US) 2024-08-20 US disclosed
CN-110511278-B Anti-B7-H6 antibodies, fusion proteins, and methods of use thereof 达特茅斯大学理事会 2024-08-09 CN disclosed