Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.79 |
| ▸ | MEN1 | O00255 | 4/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.57 |
| ▸ | RGS12 | O14924 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557953 | 1.00 | EGFR (0.82) | EGFRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL14411461 | 0.91 | EGFR (1.00) | EGFRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL18292294 | 0.88 | KMT2A (1.00) | EGFRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL28553008 | 0.87 | EGFR (0.62) | EGFRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL4375310 | 0.87 | KMT2A (0.97) | EGFRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL4375313 | 0.87 | KMT2A (0.97) | EGFRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL4375314 | 0.87 | KMT2A (0.97) | EGFRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL28552139 | 0.85 | ALDH1A1 (0.77) | EGFRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL28557984 | 0.79 | EGFR (0.76) | EGFRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL13060220 | 0.75 | EGFR (0.77) | EGFRKMT2AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656372-B | P-phenylenediamine bridging compound and application thereof in preparation of medicines for treating sugar metabolism disorder diseases | 广州药本君安医药科技股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-114573476-B | Linear head-tail diamine bridging compound and application thereof in preparation of medicines for treating sugar metabolic disorder diseases | 广州药本君安医药科技股份有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-114656371-B | 1, 4-cyclohexanediamine bridged compounds and their use in the treatment of disorders of glucose metabolism | 广州药本君安医药科技股份有限公司 | 2024-03-12 | — | — | CN | disclosed |