Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | EGFR | P00533 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.55 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | NEK2 | P51955 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557953 | 0.85 | EGFR (0.82) | ALDH1A1KDM4EL3MBTL1EGFRKMT2A | |
| SCHEMBL30788166 | 0.85 | EGFR (0.82) | ALDH1A1KDM4EL3MBTL1EGFRKMT2A | |
| SCHEMBL28553008 | 0.80 | EGFR (0.62) | ALDH1A1KDM4EL3MBTL1EGFRKMT2A | |
| SCHEMBL28554525 | 0.77 | ALDH1A1 (0.67) | ALDH1A1KDM4EL3MBTL1EGFRKMT2A | |
| SCHEMBL3426368 | 0.74 | ALDH1A1 (0.62) | ALDH1A1KDM4EL3MBTL1EGFRKMT2A | |
| SCHEMBL3426371 | 0.74 | ALDH1A1 (0.62) | ALDH1A1KDM4EL3MBTL1EGFRKMT2A | |
| SCHEMBL14411461 | 0.74 | EGFR (1.00) | ALDH1A1KDM4EL3MBTL1EGFRKMT2A | |
| Hydrochloric Acid SCHEMBL3426559 | 0.74 | ALDH1A1 (0.61) | ALDH1A1KDM4EL3MBTL1EGFRKMT2A | |
| Hydrochloric Acid SCHEMBL3426556 | 0.74 | ALDH1A1 (0.61) | ALDH1A1KDM4EL3MBTL1EGFRKMT2A | |
| SCHEMBL13060204 | 0.73 | ALDH1A1 (0.74) | ALDH1A1KDM4EEGFRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656372-B | P-phenylenediamine bridging compound and application thereof in preparation of medicines for treating sugar metabolism disorder diseases | 广州药本君安医药科技股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-114573476-B | Linear head-tail diamine bridging compound and application thereof in preparation of medicines for treating sugar metabolic disorder diseases | 广州药本君安医药科技股份有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-114656371-B | 1, 4-cyclohexanediamine bridged compounds and their use in the treatment of disorders of glucose metabolism | 广州药本君安医药科技股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-114656371-A | 1, 4-cyclohexanediamine bridged compound and application thereof in preparing medicament for treating glycometabolism disorder diseases | 广州药本君安医药科技股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114656372-A | P-phenylenediamine bridged compound and application thereof in preparation of medicines for treating glycometabolism disorder diseases | 广州药本君安医药科技股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114573476-A | Linear head-tail diamine bridged compound and application thereof in preparing medicament for treating glycometabolism disorder diseases | 广州药本君安医药科技股份有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-112500314-B | Compound, preparation method thereof and application thereof in preparing medicament for treating glycometabolism disorder diseases | 广州药本君安医药科技股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-112500314-A | Compound, preparation method thereof and application thereof in preparing medicament for treating glycometabolism disorder diseases | 广州药本君安医药科技股份有限公司 | 2021-03-16 | — | — | CN | disclosed |