Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 10/20 | 0.47 |
| ▸ | JAK2 | O60674 | 9/20 | 0.47 |
| ▸ | JAK3 | P52333 | 9/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27387027 | 1.00 | JAK1 (0.47) | JAK1JAK2JAK3PIK3CDCSF1R | |
| SCHEMBL30788206 | 0.88 | JAK2 (0.45) | JAK1JAK2JAK3CRBNLRRK2 | |
| SCHEMBL27388538 | 0.88 | JAK2 (0.45) | JAK1JAK2JAK3CRBNLRRK2 | |
| SCHEMBL27387191 | 0.86 | JAK2 (0.61) | JAK1JAK2JAK3PIK3CDCSF1R | |
| SCHEMBL30788190 | 0.86 | JAK2 (0.61) | JAK1JAK2JAK3PIK3CDCSF1R | |
| SCHEMBL30788211 | 0.84 | JAK2 (0.62) | JAK1JAK2JAK3PIK3CDCSF1R | |
| SCHEMBL27387132 | 0.84 | JAK2 (0.62) | JAK1JAK2JAK3PIK3CDCSF1R | |
| SCHEMBL30788218 | 0.81 | JAK1 (0.48) | JAK1JAK2JAK3CSF1RPDPK1 | |
| SCHEMBL30788193 | 0.80 | JAK2 (0.57) | JAK1JAK2JAK3PTK2LRRK2 | |
| SCHEMBL27387022 | 0.80 | JAK2 (0.57) | JAK1JAK2JAK3PTK2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024035771-A2 | ULK3 INHIBITORS AND USES THEREOF | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2024-02-15 | — | — | WO | disclosed |