Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125954 | 1.00 | LMNA (0.44) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL30788472 | 0.89 | ALDH1A1 (0.41) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL29125772 | 0.89 | ALDH1A1 (0.41) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL29125714 | 0.83 | CYP1A2 (0.55) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL30788510 | 0.83 | CYP1A2 (0.55) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL29126003 | 0.81 | TSHR (0.49) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL29125948 | 0.80 | KMT2A (0.53) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL30788482 | 0.79 | ALDH1A1 (0.42) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL29126012 | 0.79 | ALDH1A1 (0.42) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL30788513 | 0.79 | KMT2A (0.50) | LMNAMAPTALDH1A1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |