Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.36 |
| ▸ | CLPP | Q16740 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30788572 | 0.80 | MAOB (0.43) | MAOBADORA2AADORA1SMN1; SMN2TDP1 | |
| SCHEMBL1909503 | 0.79 | SCD (0.55) | L3MBTL1SMN1; SMN2SCDTAS2R8KMT2A | |
| SCHEMBL30788550 | 0.79 | SCD (0.43) | MAOBADORA2AADORA1SMN1; SMN2TDP1 | |
| SCHEMBL30788640 | 0.74 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2LMNAPKMMAPT | |
| SCHEMBL1909686 | 0.73 | RAB9A (0.61) | L3MBTL1SMN1; SMN2SCDLMNATSHR | |
| SCHEMBL1909621 | 0.71 | HDAC1 (0.49) | L3MBTL1SMN1; SMN2SCD | |
| SCHEMBL240604 | 0.70 | HDAC1 (0.53) | L3MBTL1SMN1; SMN2SCDLMNATSHR | |
| SCHEMBL244590 | 0.70 | SCD (0.50) | L3MBTL1SCDLMNA | |
| SCHEMBL4177453 | 0.69 | ADORA2A (0.51) | MAOBADORA2AADORA1SMN1; SMN2TDP1 | |
| SCHEMBL244363 | 0.68 | SCD (0.66) | L3MBTL1SMN1; SMN2SCDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581029-A1 | CYCLIC UREA THIAZOLYL COMPOUNDS FOR TREATMENT OF HSV | Assembly Biosciences, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024049760-A1 | CYCLIC UREA THIAZOLYL COMPOUNDS FOR TREATMENT OF HSV | ASSEMBLY BIOSCIENCES, INC. (US) | 2024-03-07 | — | — | WO | disclosed |