Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31055344 | 0.77 | CYP19A1 (0.55) | NPC1MAPTHTTRAB9AMITF | |
| SCHEMBL30668144 | 0.77 | CYP19A1 (0.44) | NPC1MAPTHTTRAB9AMITF | |
| SCHEMBL30763440 | 0.65 | NPC1 (0.52) | NPC1MAPTHTTRAB9AMITF | |
| Isocentratherin SCHEMBL29375570 | 0.64 | NPC1 (0.58) | NPC1MAPTHTTRAB9AMITF | |
| Molephantinin SCHEMBL29001111 | 0.64 | NPC1 (1.00) | NPC1MAPTHTTRAB9AMITF | |
| Tomenphantin A SCHEMBL27945189 | 0.63 | FNTA (0.61) | NPC1MAPTHTTRAB9AFNTA | |
| Tomenphantin A SCHEMBL6484758 | 0.63 | FNTA (0.61) | NPC1MAPTHTTRAB9AFNTA | |
| Tomenphantin A SCHEMBL30039069 | 0.63 | FNTA (0.61) | NPC1MAPTHTTRAB9AFNTA | |
| Eupalinilide B SCHEMBL30595110 | 0.62 | MAPT (0.42) | NPC1MAPTHTTRAB9AMITF | |
| Ludartin SCHEMBL29556149 | 0.60 | CYP19A1 (1.00) | NPC1MAPTHTTRAB9ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117414380-A | Application of grandma hederacea in preparing anti-tumor medicament | 沈阳药科大学 | 2024-01-19 | — | — | CN | claimed |
| CN-117414380-A | Application of grandma hederacea in preparing anti-tumor medicament | 沈阳药科大学 | 2024-01-19 | — | — | CN | disclosed |