Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571626 | 0.83 | SLC9A1 (0.53) | SLC9A1HDAC4KDM1AMAOAMAOB | |
| SCHEMBL12498720 | 0.80 | HDAC4 (0.53) | SLC9A1HDAC4 | |
| SCHEMBL15768718 | 0.80 | HDAC4 (0.53) | SLC9A1HDAC4 | |
| SCHEMBL15768691 | 0.78 | HDAC4 (0.55) | SLC9A1HDAC4SLC6A4 | |
| SCHEMBL12497988 | 0.78 | HDAC4 (0.55) | SLC9A1HDAC4SLC6A4 | |
| SCHEMBL15768815 | 0.78 | HDAC4 (0.55) | SLC9A1HDAC4 | |
| SCHEMBL12499694 | 0.78 | HDAC4 (0.55) | SLC9A1HDAC4 | |
| SCHEMBL15768592 | 0.77 | HDAC4 (0.58) | SLC9A1HDAC4 | |
| SCHEMBL15768593 | 0.77 | HDAC4 (0.58) | SLC9A1HDAC4 | |
| SCHEMBL3288310 | 0.76 | SLC9A1 (0.68) | SLC9A1KDM1AMAOAMAOBSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565228-A2 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | Kojin Therapeutics, Inc. (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024030960-A2 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | Kojin Therapeutics, Inc. (US) | 2024-02-08 | — | — | WO | disclosed |