Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.53 |
| ▸ | CTSS | P25774 | 5/20 | 0.53 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300194 | 0.88 | CTSK (0.60) | CTSKCTSSPPARAPPARGKLK5 | |
| SCHEMBL23176824 | 0.86 | CTSK (0.58) | CTSKCTSSKLK5CTSBCTSL | |
| SCHEMBL7032329 | 0.86 | CTSK (0.68) | CTSKCTSSPPARAPPARGKLK5 | |
| SCHEMBL12560624 | 0.86 | CTSK (0.68) | CTSKCTSSPPARAPPARGKLK5 | |
| SCHEMBL6344320 | 0.86 | CTSK (0.68) | CTSKCTSSPPARAPPARGKLK5 | |
| SCHEMBL30788980 | 0.85 | CTSK (0.54) | CTSKCTSSPPARAPPARGKLK5 | |
| SCHEMBL30788866 | 0.84 | PPARA (0.53) | CTSKCTSSPPARAPPARGKLK5 | |
| SCHEMBL8146699 | 0.83 | PPARA (0.69) | CTSKCTSSPPARAPPARGPPARD | |
| SCHEMBL7541179 | 0.83 | PPARA (0.54) | CTSKCTSSPPARAPPARGKLK5 | |
| SCHEMBL7541173 | 0.83 | PPARA (0.54) | CTSKCTSSPPARAPPARGKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565228-A2 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | Kojin Therapeutics, Inc. (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024030960-A2 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | Kojin Therapeutics, Inc. (US) | 2024-02-08 | — | — | WO | disclosed |