Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | KYNU | Q16719 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541179 | 1.00 | PPARA (0.54) | PPARAPPARGSYKKLK7PPARD | |
| SCHEMBL7542832 | 0.89 | PPARA (0.65) | PPARAPPARGSYKPPARDKYNU | |
| SCHEMBL7542840 | 0.89 | PPARA (0.65) | PPARAPPARGSYKPPARDKYNU | |
| SCHEMBL23961328 | 0.84 | KYNU (0.62) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL28433137 | 0.84 | PPARA (0.57) | PPARAPPARGSYKKLK7PPARD | |
| SCHEMBL28433139 | 0.84 | PPARA (0.57) | PPARAPPARGSYKKLK7PPARD | |
| SCHEMBL30788980 | 0.84 | CTSK (0.54) | PPARAPPARGSYKKLK7PPARD | |
| SCHEMBL17446725 | 0.83 | PPARA (0.55) | PPARAPPARGSYKKLK7PPARD | |
| SCHEMBL1429859 | 0.83 | PPARA (0.54) | PPARAPPARGSYKKLK7PPARD | |
| SCHEMBL12243946 | 0.83 | KYNU (0.60) | KYNUALDH1A1ALOX15FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |