SCHEMBL30790664

SCHEMBL30790664

Brc1cccc(/C=C/[Si](c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 1/20 0.49
ALDH1A1 P00352 3/20 0.47
MAPT P10636 3/20 0.45
MAOB P27338 3/20 0.43
MAOA P21397 2/20 0.43
NPSR1 Q6W5P4 2/20 0.40
PLAAT5 Q96KN8 1/20 0.40
PLAAT4 Q9UL19 1/20 0.40
TP53 P04637 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
SLC6A19 Q695T7 1/20 0.40
BACE1 P56817 1/20 0.40
NPC1 O15118 1/20 0.40
TSHR P16473 1/20 0.40
RAB9A P51151 1/20 0.40
HTT P42858 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP1B1 Q16678 1/20 0.39
HSD11B1 P28845 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29141686 1.00 HSD17B3 (0.49) HSD17B3ALDH1A1MAPTMAOBMAOA
SCHEMBL29141687 1.00 HSD17B3 (0.49) HSD17B3ALDH1A1MAPTMAOBMAOA
SCHEMBL8157734 0.82 MAOB (0.48) ALDH1A1MAPTMAOBMAOASMN1; SMN2
SCHEMBL699998 0.80 HSD17B3 (0.59) HSD17B3ALDH1A1MAPTMAOBMAOA
SCHEMBL699999 0.80 HSD17B3 (0.59) HSD17B3ALDH1A1MAPTMAOBMAOA
SCHEMBL29141683 0.78 MAOB (0.50) ALDH1A1MAOBMAOATP53SMN1; SMN2
SCHEMBL29141684 0.78 MAOB (0.50) ALDH1A1MAOBMAOATP53SMN1; SMN2
SCHEMBL30790666 0.78 MAOB (0.50) ALDH1A1MAOBMAOATP53SMN1; SMN2
SCHEMBL30790665 0.78 NFE2L2 (0.66) NPC1RAB9ACYP2D6
SCHEMBL29141714 0.78 NFE2L2 (0.66) NPC1RAB9ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430128-B Preparation method and application of copper-doped ZSM-5 zeolite molecular sieve containing mesoporous structure 常州大学 2025-04-25 CN disclosed
CN-117430128-A Preparation method and application of copper-doped ZSM-5 zeolite molecular sieve containing mesoporous structure 常州大学 2024-01-23 CN disclosed