Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 7/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26156898 | 0.82 | SMARCA2 (0.46) | SMARCA2SMARCA4CHRM4CHRM1PSEN1 | |
| SCHEMBL16684915 | 0.81 | SMARCA2 (0.47) | SMARCA2SMARCA4SUV39H2PSEN1PSEN2 | |
| Hydrochloric Acid SCHEMBL2275791 | 0.80 | SMARCA2 (0.46) | SMARCA2SMARCA4SUV39H2PSEN1PSEN2 | |
| Hydrochloric Acid SCHEMBL16684752 | 0.80 | SMARCA2 (0.46) | SMARCA2SMARCA4SUV39H2PSEN1PSEN2 | |
| SCHEMBL4391755 | 0.80 | CHRNB2 (0.58) | CHRM4SUV39H2HRH4 | |
| SCHEMBL786061 | 0.79 | HRH4 (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30790732 | 0.79 | SUV39H2 (0.40) | SUV39H2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL15114940 | 0.78 | ADRB1 (0.56) | SMARCA2SMARCA4HRH4 | |
| SCHEMBL14788209 | 0.78 | MAPK8 (0.46) | CHRM4PDE10A | |
| SCHEMBL16691292 | 0.78 | PSEN1 (0.50) | SMARCA2SMARCA4CHRM4PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260055108-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | HUTCHMED LTD (CN) | 2026-02-26 | — | — | US | disclosed |
| EP-4581032-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | HUTCHMED Limited (CN) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024046457-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | HUTCHMED LIMITED (CN) | 2024-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260055108-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | CBR1, CNR1, CBR3 | SMARCA2 3011/4885SMARCA4 3070/4885CHRM4 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.