Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.44 |
| ▸ | MAOA | P21397 | 9/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27842888 | 1.00 | MAOB (0.44) | MAOBMAOAADRA2BADRA2CADRA1A | |
| SCHEMBL27759010 | 1.00 | MAOB (0.44) | MAOBMAOAADRA2BADRA2CADRA1A | |
| SCHEMBL30995707 | 0.91 | MAOB (0.51) | MAOBMAOAADRA2BADRA2CADRA1A | |
| SCHEMBL1051972 | 0.91 | MAOB (0.51) | MAOBMAOAADRA2BADRA2CADRA1A | |
| Tartaric Acid SCHEMBL30356997 | 0.86 | MAOB (0.36) | MAOBMAOAADRA2BADRA2CADRA1A | |
| Cadaverine Tartrate SCHEMBL28970956 | 0.86 | MAOB (0.36) | MAOBMAOAADRA2BADRA2CADRA1A | |
| SCHEMBL29004430 | 0.77 | SIGMAR1 (0.40) | ADRA2BADRA2CADRA1ABCHEACHE | |
| SCHEMBL28762120 | 0.74 | SIGMAR1 (0.49) | MAOABCHEACHEHTR6HTR2A | |
| SCHEMBL28661848 | 0.74 | SIGMAR1 (0.41) | ADRA2BADRA2CADRA1AHTR6HTR2A | |
| SCHEMBL27670715 | 0.74 | SIGMAR1 (0.49) | MAOABCHEACHEHTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947675-B | Rasagiline intermediate and preparation method and application thereof | 博济医药科技股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-115947675-A | Rasagiline intermediate and preparation method and application thereof | 博济医药科技股份有限公司 | 2023-04-11 | — | — | CN | disclosed |
| US-9820937-B2 | Pharmaceutical composition formulated for pre-gastric absorption of monoamine oxidase B inhibitors | R.P. SCHERER TECHNOLOGIES, LLC (US) | 2017-11-21 | — | — | US | disclosed |
| CN-102276491-B | Method for preparing midbody of rasagiline | CHIRAL QUEST BIOCHEMICAL SUZHOU CO LTD | 2014-03-05 | — | — | CN | disclosed |
| CN-102464589-A | Preparation method of rasagiline, mesylate and intermediate thereof | CHIRAL QUEST SUZHOU CO LTD | 2012-05-23 | — | — | CN | disclosed |
| CN-102276491-A | Method for preparing midbody of rasagiline | — | 2011-12-14 | — | — | CN | disclosed |
| US-20100227933-A1 | PHARMACEUTICAL COMPOSITION FORMULATED FOR PRE-GASTRIC ABSORPTION OF MONOAMINE OXIDASE B INHIBITORS | BREWER FRANCESCA MARY | 2010-09-09 | — | — | US | disclosed |
| CN-101381314-A | Preparation method of (R)-(+)-N-propargyl-1-indan amines | CHENGDU HEALTHCARE PHARMACEUTI (CN) | 2009-03-11 | — | — | CN | disclosed |
| EP-0814789-B2 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOAMINE OXIDASE B INHIBITORS | SCHERER TECHNOLOGIES INC R P (US) | 2008-01-09 | — | — | EP | disclosed |
| US-20050106241-A1 | Pharmaceutical composition formulated for pre-gastric absorption of monoamine oxidase B inhibitors | CATALENT PHARMA SOLUTIONS, INC. | 2005-05-19 | — | — | US | disclosed |
| EP-0814789-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOAMINE OXIDASE B INHIBITORS | SCHERER TECHNOLOGIES INC R P (US) | 2003-05-28 | — | — | EP | disclosed |
| US-20010021722-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOAMINE OXIDASE B INHIBITORS | BREWER FRANCESCA MARY (GB) | 2001-09-13 | — | — | US | disclosed |
| EP-0814789-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOAMINE OXIDASE B INHIBITORS | R.P. Scherer Limited (GB) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996026720-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOAMINE OXIDASE B INHIBITORS | R.P. SCHERER LIMITED (GB) | 1996-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010021722-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOAMINE OXIDASE B INHIBITORS | MAOB, MAOA, COMT | MAOB 1/4885MAOA 2/4885ADRA2B 68/4885 |
| US-20100227933-A1 | PHARMACEUTICAL COMPOSITION FORMULATED FOR PRE-GASTRIC ABSORPTION OF MONOAMINE OXIDASE B INHIBITORS | MAOB, MAOA, COMT | MAOB 1/4885MAOA 2/4885ADRA2B 113/4885 |
| US-20050106241-A1 | Pharmaceutical composition formulated for pre-gastric absorption of monoamine oxidase B inhibitors | MAOB, MAOA, COMT | MAOB 1/4885MAOA 2/4885ADRA2B 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.