Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | ULK1 | O75385 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23356121 | 1.00 | EGFR (0.43) | EGFRKDRULK1RIPK1AR | |
| SCHEMBL30791247 | 0.88 | EGFR (0.35) | EGFRKDRULK1EPHX2PIK3CA | |
| SCHEMBL23369587 | 0.88 | DHODH (0.42) | EGFRKDRULK1PIK3CAPIK3CB | |
| SCHEMBL23356058 | 0.88 | EGFR (0.35) | EGFRKDRULK1EPHX2PIK3CA | |
| SCHEMBL30791216 | 0.85 | SGK1 (0.33) | KDRSGK1 | |
| SCHEMBL23356099 | 0.85 | SGK1 (0.33) | KDRSGK1 | |
| SCHEMBL30791280 | 0.84 | TRPA1 (0.34) | EGFRKDRULK1SGK1PIK3CA | |
| SCHEMBL23356081 | 0.84 | TRPA1 (0.34) | EGFRKDRULK1SGK1PIK3CA | |
| SCHEMBL23356027 | 0.83 | GRM4 (0.47) | EGFRKDRSGK1 | |
| SCHEMBL30791242 | 0.83 | GRM4 (0.47) | EGFRKDRSGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313232-B | Novel heterocyclic derivatives | JW中外制药公司 | 2024-03-08 | — | — | CN | disclosed |