Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | SGK1 | O00141 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ULK1 | O75385 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23356081 | 1.00 | TRPA1 (0.34) | TRPA1PTK2SGK1PIK3CAPIK3CB | |
| SCHEMBL23356066 | 0.85 | TRPA1 (0.32) | TRPA1SGK1KDREGFR | |
| SCHEMBL30791202 | 0.85 | TRPA1 (0.32) | TRPA1SGK1KDREGFR | |
| SCHEMBL30791233 | 0.84 | EGFR (0.43) | SGK1PIK3CAPIK3CBPIK3CGKDR | |
| SCHEMBL23356121 | 0.84 | EGFR (0.43) | SGK1PIK3CAPIK3CBPIK3CGKDR | |
| SCHEMBL23356009 | 0.82 | OPRM1 (0.38) | PTK2SGK1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL30791283 | 0.82 | OPRM1 (0.38) | PTK2SGK1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL23356058 | 0.82 | EGFR (0.35) | PIK3CAPIK3CBPIK3CGKDREGFR | |
| SCHEMBL23369587 | 0.82 | DHODH (0.42) | PIK3CAPIK3CBPIK3CGKDRIKBKB | |
| SCHEMBL30791247 | 0.82 | EGFR (0.35) | PIK3CAPIK3CBPIK3CGKDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313232-B | Novel heterocyclic derivatives | JW中外制药公司 | 2024-03-08 | — | — | CN | disclosed |