Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29420699 | 1.00 | KIF11 (0.62) | KIF11PTPN1PTPN5TSHRALDH1A1 | |
| SCHEMBL24106776 | 0.98 | KIF11 (0.67) | KIF11PTPN1PTPN5TSHRALDH1A1 | |
| SCHEMBL26821704 | 0.98 | KIF11 (0.67) | KIF11PTPN1PTPN5TSHRALDH1A1 | |
| Cyanide SCHEMBL27967216 | 0.94 | KIF11 (0.56) | KIF11PTPN1PTPN5TSHRALDH1A1 | |
| SCHEMBL1263144 | 0.93 | TSHR (0.58) | KIF11TSHRALDH1A1MAOBKDM1A | |
| SCHEMBL29678302 | 0.93 | TSHR (0.58) | KIF11TSHRALDH1A1MAOBKDM1A | |
| SCHEMBL26827704 | 0.91 | MAOB (0.62) | KIF11PTPN1PTPN5TSHRMAOB | |
| Ammonia Solution, Strong SCHEMBL20472961 | 0.90 | MAOB (0.56) | KIF11TSHRALDH1A1MAOBKDM1A | |
| SCHEMBL16068255 | 0.88 | KIF11 (0.67) | KIF11PTPN1TSHRALDH1A1MAOB | |
| Urea SCHEMBL16246927 | 0.88 | KIF11 (0.67) | KIF11PTPN1PTPN5MAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109603589-B | Ag @ NH2-MIL-125/polyarylethersulfone hybridized compact reactive ultrafiltration membrane and preparation method thereof | 东北师范大学 | 2021-02-05 | — | — | CN | claimed |
| CN-110437280-A | A kind of new method preparing 2 '-iodos [1,1 '-biaryl] -2- organic phosphonate compounds | HUNAN INST SCIENCE & TECH | 2019-11-12 | — | — | CN | claimed |
| CN-106496557-A | A kind of preparation method of high transparency high temperature resistant fluorinated polyimide resin | 沈阳化工大学 | 2017-03-15 | — | — | CN | claimed |
| CN-106220848-A | Melt temperature and vitrification point difference fire resistant polyimide less than 30 degree and preparation method thereof | 深圳市惠程电气股份有限公司 | 2016-12-14 | — | — | CN | claimed |
| EP-2456435-B1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | UNIV LELAND STANFORD JUNIOR (US) | 2015-06-24 | — | — | EP | claimed |
| US-20120225862-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | AUCKLAND UNIVSERVICES LIMITED (NZ) | 2012-09-06 | — | — | US | claimed |
| EP-2456435-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | The Board of Trustees of The Leland Stanford Junior University (US) | 2012-05-30 | — | — | EP | claimed |
| WO-2011011514-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-01-27 | — | — | WO | claimed |
| CN-101463042-A | Silicon-containing benzocyclobutene resin, intermediate thereof and preparation of the resin and intermediate | CHINESE ACAD INST CHEMISTRY (CN) | 2009-06-24 | — | — | CN | claimed |
| US-7304065-B2 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | claimed |
| CN-101068773-A | Melanin concentrating hormone antagonists | PROCTER & GAMBLE (US) | 2007-11-07 | — | — | CN | claimed |
| EP-1667958-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-14 | — | — | EP | claimed |
| WO-2005033063-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-14 | — | — | WO | claimed |
| US-20050075324-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-07 | — | — | US | claimed |
| US-12551482-B2 | Aurora kinase inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-02-17 | — | — | US | disclosed |
| CN-118451569-A | Conductive adhesive, preparation method, secondary battery, battery module, battery pack and electricity utilization device | 宁德时代新能源科技股份有限公司 | 2024-08-06 | — | — | CN | disclosed |
| US-20230348509-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-02 | — | — | US | disclosed |
| EP-0837848-A1 | 4-ARYL-1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES HAVING NEUROTROPHIC AND NEUROPROTECTIVE ACTIVITY | SANOFI (FR) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997001536-A1 | 4-ARYL-1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES HAVING NEUROTROPHIC AND NEUROPROTECTIVE ACTIVITY | SANOFI (FR) | 1997-01-16 | — | — | WO | disclosed |
| US-4731450-A | Process for perfluoroalkylation of aromatic derivatives | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075324-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC1R | KIF11 4169/4885PTPN1 1383/4885PTPN5 739/4885 |
| US-12551482-B2 | Aurora kinase inhibitors | MYC, AURKA, AURKC | KIF11 389/4885PTPN1 2593/4885PTPN5 3239/4885 |
| US-20120225862-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | BRDT, NISCH, PAICS | KIF11 4044/4885PTPN1 4813/4885PTPN5 4665/4885 |
| US-20230348509-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | MLX, OCIAD1, LBR | KIF11 3131/4885PTPN1 4181/4885PTPN5 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.