Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CBLB | Q13191 | 3/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153076 | 1.00 | MAP3K5 (0.34) | MAP3K5LMNAGAAGRM2PSD | |
| SCHEMBL30792001 | 1.00 | MAP3K5 (0.34) | MAP3K5LMNAGAAGRM2PSD | |
| SCHEMBL30792046 | 0.93 | MAP3K5 (0.34) | MAP3K5LMNAGAAGRM2KCNH2 | |
| SCHEMBL24820582 | 0.93 | MAP3K5 (0.34) | MAP3K5LMNAGAAGRM2KCNH2 | |
| SCHEMBL30152957 | 0.93 | MAP3K5 (0.34) | MAP3K5LMNAGAAGRM2KCNH2 | |
| SCHEMBL24818967 | 0.90 | CBLB (0.41) | MAP3K5GRM2KCNH2CBLBALDH1A1 | |
| SCHEMBL30153054 | 0.90 | CBLB (0.41) | MAP3K5GRM2KCNH2CBLBALDH1A1 | |
| SCHEMBL30792053 | 0.90 | CBLB (0.41) | MAP3K5GRM2KCNH2CBLBALDH1A1 | |
| SCHEMBL24820737 | 0.88 | AGPAT2 (0.38) | ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL30792049 | 0.88 | AGPAT2 (0.38) | ALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |