Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 4/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CBLB | Q13191 | 6/20 | 0.31 |
| ▸ | CBL | P22681 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818926 | 0.89 | HPGD (0.38) | ESR2HPGDMAPTKDM4EALDH1A1 | |
| SCHEMBL24818936 | 0.85 | CBL (0.32) | CBLBCBL | |
| SCHEMBL24818935 | 0.85 | S1PR1 (0.34) | CETPS1PR1ESR2CBLBCBL | |
| SCHEMBL30152954 | 0.81 | CBLB (0.51) | CBLBCBL | |
| SCHEMBL30792112 | 0.81 | CBLB (0.51) | CBLBCBL | |
| SCHEMBL24819910 | 0.81 | CBLB (0.51) | CBLBCBL | |
| SCHEMBL24818937 | 0.79 | TRPV3 (0.33) | CBLB | |
| SCHEMBL24819809 | 0.78 | CETP (0.38) | CETPS1PR1ESR2CBLBHPGD | |
| SCHEMBL30153136 | 0.78 | CETP (0.38) | CETPS1PR1ESR2CBLBHPGD | |
| SCHEMBL24821953 | 0.76 | ESR1 (0.35) | ESR2CBLBCBLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |