Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | PDE8B | O95263 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28933439 | 0.81 | RXRA (0.36) | FGFR1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL28933441 | 0.81 | RXRA (0.36) | FGFR1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL18198891 | 0.80 | FGFR1 (0.38) | FGFR1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL29705188 | 0.80 | FGFR1 (0.38) | FGFR1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL29854877 | 0.75 | RXRA (0.37) | FGFR1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL28700991 | 0.75 | RXRA (0.37) | FGFR1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL29389829 | 0.75 | RXRA (0.37) | FGFR1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL3715963 | 0.74 | IP6K1 (0.33) | FGFR1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL28708419 | 0.74 | IP6K1 (0.35) | FGFR1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL3715961 | 0.74 | IP6K1 (0.33) | FGFR1CYP4F2CYP4A11NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072387-B | Indazole compound, pharmaceutical composition and application thereof | 暨南大学 | 2024-03-08 | — | — | CN | disclosed |