Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.63 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868603 | 1.00 | ACHE (0.63) | ACHEVKORC1TRPV1PGRHTR1A | |
| SCHEMBL868605 | 1.00 | ACHE (0.63) | ACHEVKORC1TRPV1PGRHTR1A | |
| SCHEMBL1665010 | 0.87 | AKR1C3 (0.56) | ACHEPTGS1ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL11768061 | 0.85 | ACHE (0.49) | ACHEVKORC1TRPV1PGRHTR1A | |
| SCHEMBL5868933 | 0.83 | ACHE (0.56) | ACHEPTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL5868935 | 0.83 | ACHE (0.56) | ACHEPTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL5869164 | 0.82 | ACHE (0.55) | ACHEAKR1C3AKR1C2PPARGPPARA | |
| SCHEMBL12702676 | 0.81 | BACE1 (0.56) | ACHETRPV1ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL8019435 | 0.80 | BACE1 (0.58) | ACHEALDH1A1AKR1C3AKR1C2PPARG | |
| SCHEMBL26501152 | 0.79 | ACHE (0.43) | ACHEVKORC1TRPV1PGRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100226982-A1 | Stabilized Active Ingredient Composition | DR. SUWELACK SKIN & HEALTH CARE AG (DE) | 2010-09-09 | — | — | US | disclosed |