Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26500947 | 0.98 | ACHE (0.42) | ACHETRPV1HTR1ALMNACYP1A2 | |
| SCHEMBL26501138 | 0.81 | TRPV1 (0.43) | ACHETRPV1MAPTPGRHTR1A | |
| SCHEMBL26500803 | 0.80 | KDM4E (0.46) | ACHETRPV1MAPTPGRHTR1A | |
| SCHEMBL26500818 | 0.79 | GLA (0.43) | ACHETRPV1MAPTPGRHTR1A | |
| SCHEMBL868605 | 0.79 | ACHE (0.63) | ACHETRPV1MAPTPGRHTR1A | |
| SCHEMBL3079265 | 0.79 | ACHE (0.63) | ACHETRPV1MAPTPGRHTR1A | |
| SCHEMBL868603 | 0.79 | ACHE (0.63) | ACHETRPV1MAPTPGRHTR1A | |
| SCHEMBL26500808 | 0.79 | TRPV1 (0.48) | ACHETRPV1POLBKDM4EATM | |
| SCHEMBL11575323 | 0.79 | KDM4E (0.51) | TRPV1MAPTPGRHTR1AADORA3 | |
| SCHEMBL26500837 | 0.78 | KDM4E (0.44) | ACHETRPV1MAPTICMTGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072285-A1 | ENOATE COMPOUND CONTAINING AROMATIC RING, AND PREPARATION THEREFOR AND USE THEREOF | 中国农业大学 | 2023-05-04 | — | — | WO | disclosed |