Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | GPR39 | O43194 | 3/20 | 0.50 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | FABP1 | P07148 | 1/20 | 0.45 |
| ▸ | FABP6 | P51161 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17700171 | 1.00 | HIF1A (0.51) | HIF1AGPR39KCNH3GRIN2BCXCR4 | |
| SCHEMBL797462 | 0.88 | GPR39 (0.60) | HIF1AGPR39GRIN2BCXCR4FABP1 | |
| SCHEMBL17700541 | 0.85 | GPR39 (0.54) | HIF1AGPR39GRIN2BCXCR4FABP1 | |
| SCHEMBL31610448 | 0.83 | CXCR4 (0.49) | GPR39GRIN2BCXCR4FABP1FABP6 | |
| SCHEMBL17700175 | 0.83 | GPR39 (0.56) | HIF1AGPR39GRIN2BCXCR4FABP1 | |
| SCHEMBL4720018 | 0.81 | HRH4 (0.51) | GPR39GRIN2BCXCR4FABP1FABP6 | |
| SCHEMBL29622804 | 0.79 | CYP3A4 (0.48) | HIF1AGPR39KCNH3GRIN2BCSF1R | |
| SCHEMBL13118523 | 0.79 | GRIN2B (0.57) | GPR39GRIN2BCXCR4CCNT1CDK9 | |
| SCHEMBL1225401 | 0.77 | CDK9 (0.48) | KCNH3GRIN2BCCNT1CDK9HTR1A | |
| SCHEMBL4522025 | 0.77 | CXCR4 (0.49) | GPR39GRIN2BCXCR4FABP1FABP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| EP-4580679-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | Biohaven Therapeutics Ltd. (VG) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024050389-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-07 | — | — | WO | disclosed |