Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225494 | 1.00 | IDO1 (0.50) | IDO1FPR2GRM5FAAHP2RX7 | |
| SCHEMBL1578574 | 0.85 | FAAH (0.60) | IDO1FPR2GRM5FAAHP2RX7 | |
| SCHEMBL3377748 | 0.84 | FAAH (0.52) | IDO1FPR2GRM5FAAHP2RX7 | |
| SCHEMBL2270219 | 0.84 | GRM5 (0.54) | IDO1FPR2GRM5FAAHP2RX7 | |
| SCHEMBL30794592 | 0.84 | GRM5 (0.54) | IDO1FPR2GRM5FAAHP2RX7 | |
| SCHEMBL2221951 | 0.83 | GRM5 (0.73) | IDO1FPR2GRM5FAAHP2RX7 | |
| SCHEMBL30794648 | 0.83 | GRM5 (0.73) | IDO1FPR2GRM5FAAHP2RX7 | |
| SCHEMBL16244075 | 0.83 | FAAH (0.55) | IDO1FPR2GRM5FAAHP2RX7 | |
| SCHEMBL12218396 | 0.80 | SMN1; SMN2 (0.65) | P2RX7SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL2269402 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |